Antibiotics are undoubtedly one of the most important discoveries in the history of medicine and although we are abusing them today, in many cases they simply save our lives. Just like vaccinations …
These, unfortunately, have also recently become notorious due to the irrational approach of anti-vaccination movements, but it must be remembered that it was thanks to them that we could forget about the diseases decimating us before. Interestingly, however, according to the latest research, both do not go hand in hand, because scientists have found that reducing the diversity of the human microbiome as a result of taking antibiotics can significantly reduce the effectiveness of vaccines.
Last year, a team of Australian scientists presented a study in mice that showed that antibiotics could significantly weaken the body’s immune response to vaccines. The team focused on young mice, simulating children in their first year of life, and examined in detail 5 vaccines given to infants, including meningitis and pertussis. Similar conclusions were also drawn from the 2011 Stanford University study, but only now have scientists decided to test this theory in humans.
“To our knowledge, this is the first demonstration of broad-spectrum antibiotics acting on the human body’s immune response – in this case, the vaccine, directly caused by destruction in our intestinal bacteria,” said Bali Pulendran, who is also working on the aforementioned studies from 2011. A group of 22 adults took part in the study, which took place during the 2014-2015 flu season – half of the subjects were vaccinated against influenza normally, and the others received a trio of antibiotics for five days before vaccination.
As you might have guessed, the group after antibiotics showed a significant reduction in the diversity of intestinal bacteria, but surprisingly 30 days after vaccination both groups turned out to have similar levels of flu antibodies. Scientists were able to determine then that the most likely was that both groups had previously been in contact with this strain of flu, which is why the body’s response was so good. Therefore, another group was gathered, this time choosing the participants more carefully to make sure that they had not had previous contact with the flu strains given to them.
Then it turned out that the group stuffed early with antibiotics actually showed a much lower level of flu antibodies, and the scientists learned something new. Namely, antibiotics do not affect the immune memory of our body in terms of pathogens with which we have previously had contact, but significantly affect the ability to defend against new pathogens.
In short, we have good and bad news – on the one hand, we don’t have to worry that taking antibiotics will weaken past vaccinations, but on the other, we should probably be more careful when giving up new ones, especially if we’ve recently taken antibiotics torrent websites directory. Although researchers as always claim that it is too early to finally make judgments, hiding behind the need for further tests, and for that they still encourage vaccination against influenza, even after antibiotic therapy, because in their opinion the greater the resources of our body’s immune memory, the greater a chance to deal with each subsequent pathogen more efficiently.